If you no longer have something, you experience a loss, like the loss of a favorite sock. When something lessens, or gets smaller, that's also a loss, as in weight loss. Understand the difference between lose, loss, and lost with simple definitions, grammar explanations, and example sentences for correct usage. LOSS definition: detriment, disadvantage, or deprivation from failure to keep, have, or get. See examples of loss used in a sentence. LOSS definition: 1. the fact that you no longer have something or have less of something: 2. a disadvantage caused…. Learn more. This disambiguation page lists articles associated with the title Loss. If an internal link incorrectly led you here, you may wish to change the link to point directly to the intended article. Synonyms for LOSS: absence, lack, misplacement, deprivation, mislaying, forfeiture, sacrifice, forfeit; Antonyms of LOSS: gain, acquisition, control, hands, possession, having, keeping, winner Middle English los, probably back-formation from lost, past participle of losen to lose. “Loss.” Presented as a four-panel comic with no dialogue, the strip shows Ethan entering a hospital where he sees Lilah weeping in a hospital bed after suffering a miscarriage. Buckley cited events in his life as inspiration for the comic. On June 2nd, 2008, Buckley posted a strip titled Loss, [2] in which the female lead Lilah suffers a miscarriage. The strip marked a significant change in tone from the usually comedic comic, and the poorly-executed drama of the comic spurred Ctrl+Alt+Del's significant anti- fandom to mockery. LOSS meaning: 1. the fact that you no longer have something or have less of something: 2. a disadvantage caused…. Learn more.